The invention discloses a meropenem liposome injection, which is characterized by mainly comprising the following components of: by weight, one part of meropenem, 2-8 parts of phosphatidylethanolamine, 1-5 parts of cholesterol, 0.2-1 part of polyether 188, 0.1-0.4 part of an antioxidant, and 5-10 parts of a supporting agent. The liposome injection prepared in the invention has good redissolving performance, good stability, high entrapment rate and little side-effect, can be used to raise the preparation product quality, minimize toxic and side effects and improve the bioavailability, and has remarkable curative effects.