The invention relates to a novel preparation for treating acute soft tissue injury and a preparation method thereof. In the invention, a wrench treating capsule is replaced by a Chinese medicinal transdermal absorption patch. A preparation method of a wrench treating transdermal patch is characterized by comprising the following steps of: extracting active medicaments from nine types of medicinal materials, including Chinese angelica, divaricate saposhnikovia root, bitter orange, common anemarrhena, pedate pinallia jackinthepulpit rhizome (processed), snakegourd fruit, dahurian angelica root, safflower and thunberg fritillary bulb with ethanol; adding an appropriate amount of permeation promoter and an appropriate amount of pressure-sensitive adhesive substrate; coating onto a non-woven fabric; and cutting into appropriate sizes. The novel preparation has the characteristics: the administration times are reduced, possible liver first pass effect and gastrointestinal inactivation caused by oral administration are avoided, and side effects of gastrointestinal administration are reduced.