The invention relates to a chiral synthesis method of (S)-3-amino pyrrolidine dihydrochloride. Trans-4-hydroxyl-L-proline is taken as raw materials, is first subjected to decarboxylation and then subjected to N-tert-butoxycarbonyl (N-Boc) protection and hydroxyl sulfonylurea acylation, and is then subjected to an SN2 reaction with sodium azide and configuration reversal. After azido is changed to amino through reduction by triphenylphosphine, concentrated hydrochloric acid is directly used for removal of N-Boc protection, and target products are obtained through a total of four steps of chain reactions. Raw materials of the chiral synthesis method are easy to obtain, reaction conditions are mild, post-processing is simple and convenient, and product yield is high.