The invention belongs to the technical field of hot stamping materials and particularly relates to a flat-pressing resin based barcode print ribbon. The flat-pressing resin based barcode print ribbon is composed of a tape base as well as a back coating and a heat transfer process layer which are respectively coated on the two sides of the tape base, wherein the heat transfer process layer is divided into three parts, namely, an isolation layer, a release layer and a color layer sequentially from the surface of one side of the tape base from inside to outside, and the isolation layer is manufactured from the following raw materials in percentage by weight: 10-15% of polyurethane resin and 85-90% of wax. According to the invention, the ribbon additionally provided with the isolation layer has the advantages of high adhesive force, organic solvent cleaning resistance and the like.