The invention relates to a quaternary cationic quaternary ammnonium and a synthesis method thereof. According to the synthesis method, the target product is synthesized in one step from hexamethylenetetramine and organic halide serving as materials in the absence of solvent or corresponding solve, in the presence of corresponding catalysts, under certain temperature, pressure, atmosphere protection and stirring conditions. The synthesis method has the advantages of less synthesis steps, mild reaction conditions, simpleness and convenience in operation and no pollution; the obtained target product has the characteristics of high surface activity, strong sterilizing power, wide stem grafting, low toxicity, good stability and the like. The quaternary cationic quaternary ammnonium can be used in fields of daily chemical industry, food industry, textile, material and the like.