The invention discloses an extraction method of astaxanthin from lobster heads. The extraction method includes step a, astaxanthin separation: squeezing the astaxanthin in lobster heads, and smashing the astaxanthin for reservation; step b, enzymolysis: subjecting the astaxanthin obtained in the step a to enzymolysis, and collecting precipitated oil layers; step c, extraction: extracting the oil layers obtained in the step b, and subjecting an extraction liquid to low temperature centrifugal concentration; step d, freezing to remove impurities: freezing samples obtained through step c by low temperature centrifugal concentration, and subjecting the samples to suction filtration while the samples are cold; step e, saponification protection purification: subjecting the samples obtained in step d to saponification through an alcoholic solution of alkali; and step f, column chromatography purification: subjecting the samples obtained in step e to low temperature centrifugal concentration, and purifying the samples with polyamide to obtain the astaxanthin. The extraction method of astaxanthin from lobster heads has the advantages that the production cost is low and the purification rate is high.