The present invention discloses an anti-esophageal cancer traditional Chinese medicine preparation. The raw material includes by weight: 3 parts of codonopsis pilosula, 3 parts of rhizoma atractylodis macrocephalae, 3 parts of poria cocos, 3 parts of honey-fried licorice root, 3 parts of pinellia ternate, 1.2 parts of fructus amomi, 1.2 parts elecampane inula root, 3 parts of pericarpium citri reticulatae, 3 parts of upright ladybell root, 3 parts of radix ophiopogonis, 2 parts of airpotato yam rhizome, 3 parts of oldenlandia diffusa, 3 parts of sculellaria barbata, 3 parts of inula flower, 3 parts of ruddle, 2 parts of curcuma zedoary, 3 parts of sarcandra glabra nadkai, 3 parts of radix scrophulariae, 1.5 parts of thunberg fritillary bulb, 2 parts of pummelo peel, 3 parts of seaweed, 3 parts of kelp, 2 parts of blackberry lily, and 1.5 parts of radix sophorae tonkinensis. The raw material is decocted with water, and then mixed with 4.5 parts of edible tulip, 1.5 parts of sal ammoniac, 3 parts of borax and 50 parts of honey. The esophageal cancer is originally located in esophagus, and is under the control of stomach. The main clinical manifestations of the esophageal cancer include difficult swallowing, unsmooth choking and foaming at the mouth. The disease is result from devitalized middle yang, phlegm and retained fluid blocking and fluid and humor exhaustion. The anti-esophageal cancer drug has the effects of warming the middle and restoring yang, harmonizing the stomach and tonifying the spleen, nourishing yin and engendering fluid, downbear counterflow and resolving phlegm, and softening hardness and dissipating binds; can be used for treatment of esophagus cancer; and has a protruding effect.