Continuous system and procedure of sterilization and physical stabilization of pumpable fluids, food, or other type of fluids, through ultra-high pressure homogenization (UHPH) comprising a first heat exchanger 1 which preheats the fluid at temperature Tp between 40 and 90 DEG C; an ultra-homogenizer 3 through which fluid at temperature Tp is introduced at a pressure Pu between 200 and 600MPa increasing its temperature up to a final value Tu; a second heat exchanger 4 where its cooling temperature is adjusted at value Te; an aseptic tank 5 that receives the cooled down fluid at value Te, and from which it is pumped by sterile air pressure into an aseptic packaging machine, for the packaging of the final product.