The invention provides a liquid crystal composition with a wide nematic phase and a high response speed. The liquid crystal composition is prepared from the following components in percentage by weight: 10%-50% of component A, 40%-70% of component B, 1%-30% of component C and 1%-20% of component D, wherein the sum of all the components in percentage by weight is 100%; the component A has a bicyclohexyl and terminal alkene structure and is low in birefringence, dielectric anisotropy, clearing point and the like, thereby being beneficial to improvement of the response speed of a liquid crystal material in a displayer; the component B and the component C are connected through cyclohexane and a benzene ring to serve as a skeleton and have a fluorine-containing substituent group for forming the liquid crystal nematic phase and inhibiting the generation of a smectic phase of a mixed liquid crystal material; and the component D has a polyfluoric terphenyl structure and plays a role of greatly lowering the threshold voltage of the mixed liquid crystal material. The liquid crystal composition is applicable to a liquid crystal displayer with positive dielectric anisotropy and especially applicable to a liquid crystal displayer of an IPS (In-Place Switching) mode.