The invention discloses vegetable oil body skin care lotion containing vascular endothelial growth factor active peptides. A fusion expression product of oil body proteins inlaid on the surface of an oil body and vascular endothelial cell growth factors can directly serve as an active ingredient to be used for the development of skin care products, so that a processing technology of blending the vascular endothelial growth factors and an emulsifier (or a protective agent) is simplified, and the production cost is reduced. Meanwhile, the biological activity of the vascular endothelial cell growth factor proteins can be protected, the vascular endothelial cell growth factor active peptides are located on the surface of the oil body by using the characteristics of the oil body proteins through vegetable oil body wrapping, and the vascular endothelial cell growth factor protein can be uniformly distributed in skin care lotion through an emulsification homogenizing technology and easily takes effects through the transdermal absorption effect of the oil body. The vegetable oil body skin care lotion is simple in process and low in cost and has an obvious effect.