The invention discloses a vegetable oil body skin-care emulsion containing epidermal growth factor active polypeptide. A fusion expression product of oil body protein embedded on the surface of an oil body and an epidermal growth factor can be utilized to be directly used as an active component for developing a skin-care product, so that the processing process for mixing the growth factor and an emulsifier (or protecting agent) can be simplified, and the production cost can be reduced. Furthermore, the bioactivity of the epidermal growth factor protein can be protected, the epidermal growth factor active polypeptide can be positioned on the surface of the oil body through vegetable oil body coating by utilizing the characteristic of the oil body protein, and the epidermal growth factor protein can be uniformly distributed in the skin-care emulsion by an emulsification and homogenization technology, and can be easily volatilized through the transdermal absorption of the oil body. The vegetable oil body skin-care emulsion containing epidermal growth factor active polypeptide is simple in process, remarkable in effect and low in cost.