The invention discloses a manufacturing method of a composite material laminated plate with holes. The manufacturing method comprises the following steps: a step I of forming through holes in upper and lower mould boards, manufacturing pins with corresponding dimensions corresponding to the through holes of the mould boards, wherein one end of each of the pins is a flat end, and the other end of each of the pins is machined with chamfer, and the flat end of each of the pins is inserted into the lower mould board; a step II of manufacturing and gum dipping of fiber cloths; a step III of coating a de-molding agent on the upper and lower mould boards and the pins, laminating the fiber cloths under a semi-dried state according to a preset fiber direction of the composite material laminated plate, and enabling fibers in each layer of the filter cloths to bypass pins in the lower mould board during laminating; a step IV of compounding the mould boards to carry hot-pressing and curing; and a step V of opening a mould. The manufacturing method disclosed by the invention has the advantage that fibers at holes of the composite material laminated plate are retained and reasonably distributed near the holes of the composite material laminated plate, so that strength of the composite material laminated plate with holes is far greater than that of a composite material laminated plate with holes obtained by an existing hole-making method.