The invention relates to the field of metro safety doors, in particular to a driving mechanism for sealing a metro section protection sealing partition door busbar. The driving mechanism is connected with the busbar in a metro tunnel. A sealing door is arranged in the metro tunnel, and a busbar discharging hole is formed in the middle of the sealing door. The driving mechanism for sealing the busbar comprises a profiling rubber sealing block and a pressing board arranged below the profiling rubber sealing block in a sliding mode. The profiling rubber sealing block is fixedly arranged in the busbar discharging hole, and the middle of the profiling rubber sealing block is provided with a through hole matched with the section of the busbar. The busbar penetrates through the through hole, and when the pressing board slides upwards to press the profiling rubber sealing block, the busbar is tightly wrapped by the profiling rubber sealing block to be sealed. According to the driving mechanism for sealing the metro section protection sealing partition door busbar, the busbar can be effectively sealed through the rubber sealing block and the pressing board, in addition, a manual driving manner which can save labor is adopted in a pressure board driving mechanism, and therefore the situation that power supply is lacked in emergencies and consequently, the busbar cannot be effectively sealed will not exist.