The invention provides a high pressure common rail system control method and device. When a cam shaft sensor is in a normal working state and a crank shaft rotating speed sensor is in an abnormal working state, a signal of the crank rotating speed sensor is determined and simulated through a signal of the cam shaft sensor so that an oil sprayer can be controlled to spray oil to an air cylinder. When the crank shaft rotating speed sensor is in a normal working state and the cam shaft sensor is in an abnormal working state, the air cylinder is judged through missing teeth according to the signal of the crank shaft rotating speed sensor, and a monoblock pump is randomly selected to supply oil to a pressure accumulation oil rail. If preset rail pressure is reached within a preset time period, it is proved that the monoblock pump is correctly selected, and if preset rail pressure is not reached within the preset time period, another monoblock pump needs to be selected again to set up rail pressure. When one of the cam shaft sensor and the crank shaft rotating speed sensor is abnormal, a high pressure common rail system can be effectively controlled to supply oil to the monoblock pump and spray oil to an oil spraying nozzle through the signal of one sensor, and normal work of an engine is ensured.