The present invention provides a filter cleaning unit, a self-cleaning air purification apparatus and a use method thereof. According to the present invention, a dust suction pipe can be laterally installed on the side of a filter through an installation rack, and can be provided for removing substances absorbed on the filter through suction force, such that online cleaning regeneration can be performed on the filter in the air purification apparatus without frequent replacement of the filter so as to reduce cost and protect the environment and personnel safety; and with the adopted light source module and the adopted heating module, the filter online cleaning prompt signal can be provided so as to avoid misoperation generation, and the light wave effect and the heat accumulation effect are utilized, such that suspended micro particles are aggregated, and the particle size is increased so as to be effectively intercepted by filter, such that purposes of rapid micro particle aggregation and harmful substance reduction are achieved, and the purification effect is significantly improved.