The invention discloses an installation method for a high-speed centrifugal separation device. The installation method comprises the following steps of: step 1, measuring the diameter of the base of the high-speed centrifugal separation device; step 2, producing a base support with a diameter which is identical to the diameter of the base according to the measured diameter of the base; step 3, placing the base support on a foundation surface and temporarily fixing; step 4, hoisting the high-speed centrifugal separation device on the base support, and installing in place; step 5, horizontally adjusting the high-speed centrifugal separation device, and fixing the separation device after the adjustment is finished. According to the installation method for the high-speed centrifugal separation device disclosed by the invention, the problems of low installation efficiency and low quality of the high-speed centrifugal separation device are effectively solved, and the installation is simple, convenient, safe and reliable, thus guaranteeing the safety and quality of engineering construction. Meanwhile, lots of cost is saved, and the installation method is economic, reasonable and advanced in technology.