The present invention relates to an SPR sensor cell and an SPR sensor with high detection sensitivity. The SPR sensor cell of the present invention comprises a detection part, and a sample arrangement part adjoining the detection part. The detection part comprises an underclad layer, a core layer which is disposed such that at least a part thereof adjoins the underclad layer, a metal layer for coating the core layer, and a coating layer for coating the metal layer. The respective coating layer is formed of a material which has a band gap (Eg) of over 1.0 eV and below 7.0 eV, and an index of refraction of the coating layer is higher than an index of refraction of the core layer.