The invention relates to a low-friction hybrid support guide sleeve hydraulic cylinder. According to the technical scheme, three I-shaped hybrid oil grooves (8) are evenly formed in a hole wall of a guide sleeve (4), the middle vertical groove body of each I-shaped groove is axially arranged, namely the middle vertical groove body of each I-shaped groove is an axial oil groove, and the two symmetrical horizontal groove bodies communicated with the two ends of the corresponding axial oil groove are arranged in the peripheral direction, namely the horizontal groove bodies of each I-shaped groove are peripheral oil grooves; an oil inlet (9) is formed in the middle of each hybrid oil groove (8) in the radial direction, a pressure measuring hole (10) is formed in one side of the part, located on the bottom of the corresponding hybrid oil groove (8), of each oil inlet (9) in the radial direction, two static pressure support grooves (13) are symmetrically arranged between the hybrid oil grooves (8), an annular oil drainage groove (6) is formed in one side of each hybrid oil groove (8) and is close to one side of an end cover (5), and an oil drainage hole (7) is formed in the bottom of each annular oil drainage groove (6) in the radial direction. The low-friction hybrid support guide sleeve hydraulic cylinder has the advantages of being low in friction, light in abrasion, high in frequency response, high in reliability, long in service life, capable of facilitating piston deviation rectification, simple in structure, and convenient to dismantle.