The invention discloses a large-curvature spherical multilayer split rubber metal joint which is a rubber metal compounded flexible connection noise reduction element. The large-curvature spherical multilayer split rubber metal joint comprises a metal outer sleeve, a metal spacer bush, an elastic rubber body and a metal spindle, wherein the metal outer sleeve, the metal spacer bush and the metal spindle are vulcanized into a large-curvature spherical whole body through the elastic rubber body; the elastic rubber body is divided into multiple layers by the metal spacer bush in the vulcanizing process and is divided into multiple sections; the split slit positions of the metal outer sleeve, the metal spacer bush and the metal spindle are kept consistent. The rubber metal joint is high in endurance quality, has high radial and axial stiffness and small deflection and torsional rigidity and can be widely applied to the field of suspension of railway vehicles.