The invention relates to a three-dimensional target geologic body interpretation method based on horizontal navigation. The three-dimensional target geologic body interpretation method based on horizontal navigation includes the following steps that (1), seismic data for target geologic body interpretation are processed in an interpretative mode, and a seismic data volume fully highlighting geologic body information is obtained; (2), horizon slices near a target geologic body are extracted on the seismic data volume under the restraint of fault interpretation and horizon interpretation, and the horizon slices serve as horizontal navigation slices for target geologic body interpretation; (3), section interpretation of the target geologic body is carried out, section interpretation results are projected on seismic sections extracted in the direction perpendicular to the target geologic body strike, and the section interpretation in the direction perpendicular to the target geologic body strike is finished; (4), the seismic sections are extracted in a rolling mode step by step in the direction perpendicular to the target geologic body strike, and the section interpretation of the target geologic body is finished until all the seismic sections of the geologic body within the whole area is finished; (5), interpretation results of all the seismic sections are projected to the planes of the navigation slices, and the target geologic body is interpreted; (6), the steps (3)-(5) are carried out repeatedly until interpretation of all the seismic sections of the target geologic body within the whole area is finished.