The invention relates to the technical field of agriculture, industry and pharmacy and provides a 2-mercapto benzothiazole derivative synthetic method. According to the 2-mercapto benzothiazole derivative synthetic method, 2-mercapto benzothiazole derivatives are synthesized by take 2-halogen phenylamine, carbon disulfide and inorganic metal sulfide as the raw materials and through catalysis of copper salt. The method comprises dissolving the 2-halogen phenylamine, the inorganic metal sulfide and copper salt catalyst inside an appropriate solvent, adding the carbon disulfide inside the mixture for recreation under 50-110 DEG C for a certain time and performing purification treatment to obtain the 2-mercapto benzothiazole derivatives. The 2-mercapto benzothiazole derivative synthetic method with the copper-catalyzed carbon disulfide is rapid and efficiency, by taking the nontoxic, cheap and easily-obtained copper salt as the catalyst, omits ligand for recreations, and has the advantages of being high in yield rate, mild in conditions, low in the amount of by-products and the like.