The invention discloses a medical hemostat clamping force measuring device comprising a measuring platform used for fixing a hemostat, a pressure sensor disposed on a force bearing part of the hemostat, an adjustable resistor partial pressure interface module connected with the pressure sensor, a double-channel analog-digital signal interface module connected with the adjustable resistor partial pressure interface module, and a computer connected with the double-channel analog-digital signal interface module. The measuring method based on the above device mainly comprises two steps of marking of the pressure sensor and clamping force measuring of the medical hemostat. The medical hemostat clamping force measuring device and the measuring method are advantageous in that by simulating the state of the corresponding blood vessel, the values of the forces of closing the different positions of the blood vessel of the hemostat can be measured in a simulated manner, and therefore the structure is reasonable, the operation is simple and convenient, and the data is reliable; the device is suitable for being used in the occasions such as product detection, technical research and development, and clinic of the production enterprises, the educational scientific researches, and the clinical fields; and in order to improve the production quality and the utilization effect of the hemostat, the scientific and the statistical analysis real data can be provided.