The invention discloses a comprehensive evaluation system and a comprehensive evaluation method of a smart distribution grid. The system comprises a basic data input module, a scheme grading module, a scheme comparison module, a data input and output module, a database and an operating system, wherein the comprehensive evaluation system is based on the operating system; the basic data input module is used for inputting basic data formed by all microcosmic evaluation indexes into the system, the scheme grading module is used for newly building grading results and selecting criteria and weights to grade, the scheme comparison module is used for finishing the data comparison under the same criterion and weight and the data input and output module is used for respectively inputting and outputting scheme data, criterion data and weight data. Compared with the prior art, according to the comprehensive evaluation system, the criterion and weight can be adjusted according to the specific demands of different areas so as to perform evaluation which meets an actual condition, and references can be provided for the construction and transformation and near-optimal operation of the smart distribution grid.