The invention discloses a steering control device of a vehicle. The steering control device comprises a steering wheel, a first steering shaft and a second steering shaft. The first steering shaft is connected with the steering wheel and is coaxial with the steering wheel, and the second steering shaft is coaxial with the first steering shaft and is detachably connected with the first steering shaft by a first shaft connecting mechanism. The steering control device of the vehicle has the advantages that the first steering shaft is detachably connected with the second steering shaft, and the first shaft connecting mechanism can be detached when a driver is jammed by the steering wheel due to collision accidents of the vehicle, so that the first steering shaft and the steering wheel can be separated from the second steering shaft, the steering wheel can be conveniently and quickly removed, injury to the driver due to the steering wheel can be relieved, escape chances can be increased, and the service safety can be improved.