The invention discloses a pre-warning method for a heavy-load comprehensive inspection vehicle and a pre-warning system used for the heavy-load comprehensive inspection vehicle. The method and the system are characterized in that the pre-waning method includes the steps that (S1) a local database reads warning data from at least one detection system and stores the data, wherein the warning data include information related to detection; (S2) a data processing module reads the warning data stored in the local database, and contact information of a responsible object related to the warning data is found from a pre-stored look-up table according to the information related to detection; (S3) an information transmission module receives the warning data and the contact information, and the warning data are sent to a mobile terminal corresponding to the contact information in a short message mode. By means of the pre-warning method, real-time automatic reading, unified processing and forwarding of the warning data of different detection systems are achieved, the real-time pre-warning function is achieved, and operation safety of a heavy-load railway is effectively guaranteed.