The invention provides a Chinese herbal medicine compound preparation. The Chinese herbal medicine compound preparation is characterized by comprising, by weight, 8-30 parts of sedum aizoon, 2-20 parts of conocephalum conicum, 2-20 parts of liverwort, 6-20 parts of radix paeoniae alba and 1-10 parts of sphagnum moss. The Chinese herbal medicine compound preparation further comprises acceptable pharmaceutical adjuvants in pharmacy, and the acceptable pharmaceutical adjuvants include medical carriers, diluents, excipients and the like. The Chinese herbal medicine compound preparation can be prepared into tablets, capsules, linimentum, paste, coating agents, emulsions, nanoparticle emulsions, powder injections, injections and the like. According to another implementing scheme, the invention provides application of the Chinese herbal medicine compound preparation or a pharmaceutical composition to treatment of the bee venom, scorpion venom and snake venom. According to another implementing scheme, the invention provides application of the Chinese herbal medicine compound preparation or the pharmaceutical composition to preparing medicines for treating the bee venom, the scorpion venom and the snake venom. The Chinese herbal medicine compound preparation has the beneficial effects that the effects of treating the bee venom, the scorpion venom and the snake venom are achieved; the evolution speed of the disease course of a patient is decreased; time is won for rescuing; the difficulty that the effective medicines for treating the bee venom are in lack on clinic at present is overcome; and the application prospect is wide.