The invention relates to a fry cultivation method, in particular to an acipenser dabryanus fry start feeding and domesticating method. According to the method, acipenser dabryanus is fed in different basins and fed with fodder, after melanin in intestinal tracts of the acipenser dabryanus is exhausted completely, the tubificidae feeding frequency is gradually improved, then mixture of chopped tubificidae and powder fodder is fed to the acipenser dabryanus, then the acipenser dabryanus is divided to different basins again and fed with the mixture of the tubificidae and powder fodder, then the acipenser dabryanus is fed with micro encapsulated fodder, and finally the acipenser dabryanus which grows well are transferred to an outdoor pool to be fed gradually. According to the acipenser dabryanus fry start feeding and domesticating method, the start feeding time of acipenser dabryanus fry and fry domesticating and culturing operation are mastered, fodders of different specifications and varieties are fed to the acipenser dabryanus according to different stages, and in the culture process of the acipenser dabryanus fry, it is guaranteed that the fodder is rich, the environment is stable, diseases are reduced, the purpose of large-scale fry culture is achieved, main constraints are domesticated, and the start feeding rate, the growing speed and the survival rate of the acipenser dabryanus are improved.