The invention belongs to the technical field of well drilling and discloses an underground natural gas storage injection-production pipe column designing method. By comprehensively considering the influence on a pipe column from self weight of a pipe body, the temperature effect, the pressure effect and the friction effect generated by fluid flowing, on the basis of design of an existing pipe column, compression loads are considered and matched with the compression efficiency of a pipe column connector to design an underground natural gas storage injection-production pipe column, it is ensured that the compression efficiency of a connector of the designed pipe column meets the operation compression load and sealing requirements, and meanwhile as the triaxial stress of the pipe column is considered for design, the overall structural intensity of the injection-production pipe column can meet the operation load requirement. The underground natural gas storage injection-production pipe column designing method not only can meet the airtightness under stretching loads, but also can meet the airtightness of the pipe column after stretching and compression loads interchange, improve the sealing performance of the pipe column under the interchanged loads and ensure long-term safety operation of the injection-production pipe column.