The invention relates to a 2-pyridyl benzimidazole palladium copper heteronuclear compound, the general formula of which is shown as the specification. Specifically, X is Cl<->, Br<-> or I<->; L is a tertiary phosphine ligand; P is a diphosphine ligand; R and R1 can be -H, -CH3, -C2H5 or -OCH3; and R is at any position of aromatic ring 7-10, and R1 is at any position of pyridine ring 3-5. The compound can serve as a bimetallic catalyst to catalyze the three-component reaction of 2-acetylpyridine, 2-amino halogenated benzylalcohol and arylboronic acid so as to synthesize a 2-pyridyl quinoline derivative.