The invention relates to anti-radiation light-reflecting self-luminescent artificial leather comprising a base layer (1) and a surface layer (2), which are bonded to each other. A metal fiber layer (3) is formed on a surface of the surface layer (2). A plurality of reflective stripes (4) are disposed on the metal fiber layer (3). An outer surface of the base layer is covered with a luminescent body which is a rare earth long-afterglow luminescent body. The artificial leather has a function of reflecting light and meanwhile has an effect of radiation resistance. The artificial leather is self-luminescent without external lights and is wider in available scope.