The invention provides a digitalized high voltage power source for a movable high-frequency X-ray machine. An STM 32F103 controller is connected with a high voltage drive circuit module, a filament current drive module, a peripheral input information collecting module, a CAN bus communication module, a power source front-stage processing circuit, a peripheral input information collecting module, a CAN bus communication module, a CPLD protective circuit, a 1# voltage reference source circuit and a 2# reference source circuit and is provided with a peripheral input port. The high voltage drive circuit module and the filament current drive module are connected with a high voltage generator. According to the digitalized high voltage power source for the movable high-frequency X-ray machine, stable work of a control system of the STM32F103 controller is completed through double voltage reference sources, and unnecessary losses caused by a dead halt are effectively avoided; after the digitalized high voltage source is used for a long time, the precision of the voltage reference sources can still be accurately calibrated, drifting caused by long-term use of equipment is avoided, the logic mode that the STM 32F103 controller and the CPLD protective circuit work in parallel is used for controlling switching on and switching off of the ray machine, and a high voltage protective ray tube can be rapidly switched within 100 us when a fault is caused.