利索-全球专利检索

  1. 登录
  2. 注册
发明公开
CN104490798A 无结晶水二丁酰环磷腺苷钙晶型冻干粉针及其制备方法 有权

无结晶水二丁酰环磷腺苷钙晶型冻干粉针及其制备方法
摘要：
本发明公开了一种无结晶水二丁酰环磷腺苷钙晶型冻干粉针及其制备方法。该无结晶水二丁酰环磷腺苷钙晶型冻干粉针包含有无结晶水二丁酰环磷腺苷钙晶型和药学上可接受的载体，所述的无结晶水二丁酰环磷腺苷钙晶型在使用辐射源为Cu-Kα的粉末X-射线衍射图谱中，在衍射角2θ＝12.3°±0.2°、17.6°±0.2、21.4°±0.2°、24.7°±0.2、25.3°±0.2°和27.8°±0.2°处有特征峰。本发明的无结晶水二丁酰环磷腺苷钙晶型冻干粉针纯度高、稳定性好、制备方法简便，而且重现性好，便于工业化推广应用。
摘要（英）：

The invention discloses crystal water-free calcium dibutyryladenosine cyclophosphate crystal form freeze-dried powder injection and a preparation method thereof. The crystal water-free calcium dibutyryladenosine cyclophosphate crystal form freeze-dried powder injection comprises a crystal water-free calcium dibutyryladenosine cyclophosphate crystal form and a pharmaceutically acceptable carrier, wherein the crystal water-free calcium dibutyryladenosine cyclophosphate crystal form has characteristic peaks at the diffraction angles 2theta of 12.3+/-0.2 degrees, 17.6+/-0.2 degrees, 21.4+/-0.2 degrees, 24.7+/-0.2 degrees, 25.3+/-0.2 degrees and 27.8+/-0.2 degrees in the powdery X-ray diffraction spectrum of which the radiation source is Cu-Kalpha. The crystal water-free calcium dibutyryladenosine cyclophosphate crystal form freeze-dried powder injection disclosed by the invention is high in purity, high in stability, simple and convenient in preparation method and high in reproducibility and is convenient for industrial popularization and application.

公开/授权文献
0/0