The invention provides serum 13 type haemophilus parasuis GX0905. The serum 13 type haemophilus parasuis GX0905 is preserved in the China center for type culture collection (CCTCC) and has a preservation number of CCTCC NO: M2014125. The serum 13 type haemophilus parasuis GX0905 has stable biological properties and has strong pigling pathogenicity. The serum 13 type haemophilus parasuis GX0905 is inactivated and a pigling is inoculated with the inactivated serum 13 type haemophilus parasuis GX0905 and the serum 13 type haemophilus parasuis GX0905 produces good immunogenicity. A univalent vaccine prepared from the serum 13 type haemophilus parasuis GX0905 as a candidate vaccine strain has good safety, can produce high antibody content of a pigling, has a long persistent period, can resist homotype wild strain attack and has good immune efficacy. In clinical, the inactivated vaccine can effectively reduce Classer' sdisease occurrence, can reduce a pig farm economic loss and has immunization effects reaching or better than those of the existing commercial vaccines on the market.