The invention relates to the field of vacuum film coating, especially relates to a liquid filling system for anti-fouling film coating and particularly relates to a device suitable for accurately measuring and filling a liquid-state material. The liquid filling system is characterized by at least comprising one dosing device, wherein the dosing device is composed of a dosing controller, a displacement metering valve and a dripping valve; the chemical liquid inlet of the displacement metering valve is communicated with an anti-fouling film material chemical liquid bottle; the chemical liquid outlet of the displacement metering valve is communicated with the dripping valve; the dripping opening of the dripping valve is connected into a crucible; the dosing controller is connected with the displacement metering valve and the dripping valve and used for controlling the displacement metering valve and the dripping valve respectively. The liquid filling system disclosed by the invention has the advantage that automatic vacuum dosing without the need of opening a cavity and breaking a vacuum can be carried out.