The invention relates to a drunken driving detection system and method based on multiple sensors and a video recognition technology. The system comprises a central processing module, an alcohol sensor module, a signal processing module, a GPS module, a camera module, a voice module, a GSM module and a display and control module. Facial images are obtained and recognized through a camera, and whether the phenomenon that other people replace a driver to start an automobile so as to pass through the detection exists or not is judged; in the driving process of the automobile, the image analysis of the driver in the driving process is obtained to judge whether the driver drinks or not in combination with the multi-sensor alcohol detection; after it is detected that the driver drinks, an alarm signal is given out, automobile lock-up control is conducted, a voice prompt is given out, and the alcohol drinking behavior and the current position information of the driver are sent to relatives and friends of the driver through short messages. According to the drunken driving detection system and method, the multiple sensors and the video recognition technology are integrated to detect the alcohol drinking behavior of the driver, replacement detection and alcohol drinking detection in the driving process can be achieved, and the recognition accuracy is improved.