An array substrate, a drive method thereof and a display device are provided. According to the array substrate, a second scanning signal line is disposed corresponding to the (2N+1)th row of sub-pixels or to the (2N+2)th row of sub-pixels, or the second scanning signal line is disposed corresponding to the (N+1)th row of sub-pixels, wherein N is an integer larger than or equal to zero; each first switch element is disposed in a corresponding sub-pixel and is used for controlling on and off the corresponding sub-pixel; each second switch element is disposed in a corresponding sub-pixel group and is used for controlling on and off the a plurality of sub-pixels in the corresponding sub-pixel group; and each first scanning signal line is configured to control a plurality of the first switch elements in a row of sub-pixels while each second scanning signal line is configured to control a plurality of second switch elements in a row of sub-pixel groups. According to the display device, by reducing a resolution ratio by a half or three fourths under full-screen display, drive power consumption of a display panel is reduced without influencing displaying brightness.