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发明公开
CN105018484A CRTAP基因及其表达产物作为阿尔茨海默病的诊治靶标 有权 转让 许可 质押

CRTAP基因及其表达产物作为阿尔茨海默病的诊治靶标
摘要：
本发明公开了CRTAP基因及其表达产物可以作为阿尔茨海默病早期诊断的分子标志物，即可以通过检测受试者血液中的CRTAP基因表达水平来判断受试者是否患有阿尔茨海默病。根据本发明的研究成果，可以研发能够抑制CRTAP基因表达或者能够抑制CRTAP基因表达产物功能的药物，从而实现临床上对于阿尔茨海默病的预防和治疗。
摘要（英）：

The invention discloses a CRTAP gene and an expression product thereof capable of serving as a molecular marker for early diagnosis of Alzheimer's disease, namely judging whether a subject suffers from the Alzheimer's disease by detecting the CRTAP gene expression level in blood of the subject. According to the research result of the invention, a medicament capable of inhibiting CRTAP gene expression or inhibiting functions of a CRTAP gene expression product can be researched, thus realizing prevention and treatment of the Alzheimer's disease in clinic.

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