The invention discloses a manufacture method for a micro-electromechanical system (MEMS) lithium battery. The manufacture method comprises the steps of manufacturing a first shell and a second shell separately; and then packaging the first shell and the second shell together so as to form the battery. A cavity is formed in the first shell, and a positive electrode of the battery is integrated in the cavity. The second shell is made from a material the same as the material of the first shell. A cavity docking with the first shell is formed on the second shell. A negative electrode of the battery is integrated in the cavity. The manufacture method for the lithium battery is simple, can produce the lithium batteries in volume, lowers the production cost, and can greatly improve the consistency and reliability of battery preparation; the two dimensional structure of the electrode is changed into the three dimensional structure, so that the surface area of the electrode is greatly increased, the charge transfer resistance is reduced, the ion transference number is improved, and the energy density and power density of the battery are greatly improved; and the ion transference path can be shortened, and the battery charging time can be shortened.