The invention discloses a hybrid communication method for a communication gateway machine of a transformer substation and a main dispatching station system. The hybrid communication method comprises the following steps that: a clipping rule of each main dispatching station is pre-configured on the communication gateway machine of the transformer substation; when a target main dispatching station needs to communicate with a monitoring system of the transformer substation, the communication gateway machine of the transformer substation reads the clipping rule and clips and combines original data of the transformer substation so as to obtain data required by the target main dispatching station; a communication mode is selected according to real-time requirements of a system application of the target main dispatching station; and the data required by the target main dispatching station obtained by combination is sent to the target main dispatching station from the communication gateway machine of the transformer substation. According to the invention, information clipping and combining can be automatically completed; errors possibly due to artificial configuration can be eliminated; communication mode selection by users can be shielded through seamless switching having configurable contents; furthermore, user data transmission requirements having different real-time performances can be satisfied at the bottom layer; communication modes and contents are flexible; hardware is unnecessary to increase; and the hybrid communication method is good in compatibility and wide in application range.