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发明公开
CN105311003A 替罗非班的透皮药物制剂和给药 无效 - 撤回

替罗非班的透皮药物制剂和给药
摘要：
本发明涉及替罗非班的透皮药物制剂和给药。本发明提供了剂量可滴定的透皮给药系统，包括有效剂量的抗血栓药物，例如替罗非班或其药用盐。给药剂量与所用贴剂的大小成比例，并且能够达到60-85％的血小板抑制。该系统能够为患者的提供个性化治疗。本发明还提供了治疗需要血小板抑制的多种疾病的方法。
摘要（英）：

The invention relates to a transdermal pharmaceutical preparation and administration of tirofiban. The present invention provides a titratable transdermal drug delivery system comprising an effective dose of an antithrombotic agent, such as tirofiban, or a pharmaceutically acceptable salt thereof. The dosage of the drug delivered is proportional to the size of the patch applied and achieves 60-85% platelet inhibition. The system enables and individualized treatment for patients. Also provided are methods for the treatment of various disorders where platelet inhibition is desired.

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