Systems and methods for improving vehicle wrong-way detection including systems, sensors or features, such as those for system/network clocks, ambient light, driver impairment, automatic cruise control, blind spot warning or configurable vehicle security, either singly or in any combination therewith, may refine and/or modify the confidence level of detecting particular or potential wrong-way incidents. By modifying the confidence level, the system may change the system sensitivity by moving the cutoff point at which an alert activation takes place. The systems described above can modify the wrong-way detection sensitivity. Greater confidence, or system sensitivity, may also help enable the system to take further actions beyond a simple warning. At greater confidence levels, the system could intervene, by way of a non-limiting example, with throttle limiting, turning on the hazard lights or even bringing the vehicle to a stop.