The invention provides a threaded metal plate support and a method for fixing a pipe and a harness in a vehicle frame. The need for fixing of the heavy vehicle pneumatic pipe and the electric appliance harness can be met better. The metal plate support is provided with a threaded hole with a flange. Two or more threads are tapped in the threaded hole. A body part is provided with two or more mounting holes, and the mounting holes allow a tying belt to penetrate. During fixing, a nylon tying belt is adopted as the tying belt; according to the length of the exposed part of a bolt rod, a fixing hole is formed in the bottom, a bolt can stretch out of the threaded hole of the metal plate support; and the threaded metal plate support can be sleeved with the part, exposed out of a nut, of the bolt rod, and a body of the bolt rod is normally exposed out of the nut by more than three threads. The pipe and the harness are fixed and protected against bolt abrasion; the threaded metal plate support can be quickly sleeved with the existing bolt on the vehicle frame according to needs, assembling is convenient; and the pipe and the harness are tied flexibly; by means of the support for the pipe and the harness, the fixing problem of the pipe and the harness is solved, and the problem of friction of the pipe and the harness and the bolt on the vehicle frame is avoided; and meanwhile assembling cost is reduced.