The present invention discloses an oxygen-containing coal layer gas deoxygenation and denitrogenation liquefaction process, which comprises an oxygen-containing coal layer gas liquefaction and deoxygenation denitrogenation step and a nitrogen refrigerant circulation step, wherein the oxygen-containing coal layer gas liquefaction and deoxygenation denitrogenation step comprises that oxygen-containing coal layer gas is input into a cooling box, cooling is performed, the cooled gas enters a rectification tower to remove oxygen and nitrogen, the obtained gas enters the deep cooling section of the cooling box so as to be continuously cooled, throttling is performed, and the obtained gas enters a LNG storage tank so as to be stored, and the nitrogen refrigerant circulation step comprises that nitrogen being subjection to compression cooling through a nitrogen expansion compressor enters the cooling box, one part of the nitrogen is cooled, the cooled nitrogen is subjected to expansion throttling so as to provide the cold for the deep cooling section, the liquefaction section and the pre-cooling section, the obtained gas returns to the second-stage inlet of the nitrogen compressor, the other part of the nitrogen is liquefied, the liquefied nitrogen is throttled so as to provide the cold for a re-condenser, and the over-cooling section, the deep cooling section, the liquefaction section and the pre-cooling section of the cooling box, and the obtained gas returns to the first-stage inlet of the nitrogen compressor. According to the present invention, with the process, the applicability of domestic equipment is completely considered, the process control automation is improved, and the driving time is reduced.