The invention discloses a method for determining the dissolution rate of meisuoshuli tablets. The method comprises the steps that the meisuoshuli tablets are dissolved by taking a phosphate buffer solution with the pH valve of 8.5-8.9 as a dissolution medium to obtain a test solution; absorbancy detection is performed on the test solution, and the dissolution rate of the meisuoshuli tablets is determined on the basis of a result of the absorbancy detection. According to the method, the dissolution rate of the meisuoshuli tablets can be effectively determined, the specificity is high, the needed analysis time is short, the precision and the repeatability are good, and the accuracy is high.