The invention discloses a Meisuoshuli film coated tablet. The Meisuoshuli film coated tablet comprises Meisuoshuli and pharmaceutically acceptable auxiliary materials. The Meisuoshuli film coated tablet has the advantages of high dissolution rate, short disintegration time, small side effects, stable quality, effective performance of inflammation preventing, pain easing and fever relieving efficacy, simple preparation method, low cost, and suitableness for industrial production. The invention also provides a preparation method of the Meisuoshuli film coated tablet.