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发明公开
CN105456198A 一种荷载恩替卡韦介孔二氧化硅纳米粒及其制备方法 有权

一种荷载恩替卡韦介孔二氧化硅纳米粒及其制备方法
摘要：
本发明属于医药技术领域，涉及一种荷载恩替卡韦介孔二氧化硅纳米粒及其制备方法。本发明的荷载恩替卡韦介孔二氧化硅纳米粒，其含有恩替卡韦和介孔二氧化硅纳米粒。本发明的荷载恩替卡韦介孔二氧化硅纳米粒提高了恩替卡韦的生物利用度，并可在体内缓慢释放，并且本发明的制备方法大大提高了其载药量。
摘要（英）：

The invention belongs to the technical field of medicines, and relates to an entecavir-loaded mesoporous silica nanoparticle and a preparation method thereof. The entecavir-loaded mesoporous silica nanoparticle provided by the invention contains entecavir and mesoporous silica nanoparticle. According to the entecavir-loaded mesoporous silica nanoparticle provided by the invention, the bioavailability of the entecavir is improved; the entecavir-loaded mesoporous silica nanoparticle can be slowly released in a body; and according to the preparation method provided by the invention, the drug loading capacity is greatly improved.

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