利索-全球专利检索

  1. 登录
  2. 注册
发明公开
CN105597150A 用于修复皮肤烧伤的皮肤贴片及其制备方法 无效 - 撤回

用于修复皮肤烧伤的皮肤贴片及其制备方法
摘要：
本发明涉及一种用于修复皮肤烧伤的皮肤贴片的制备方法，包括以下步骤：分别获取脂肪干细胞和异体皮基质；将所述脂肪干细胞与水凝胶混合后接种于所述异体皮基质；其中，所述脂肪干细胞来源于皮肤烧伤患者自体；所述水凝胶是由海藻酸盐溶液和明胶溶液混合制成的。将自体脂肪干细胞负载于海藻酸盐-明胶水凝胶中，不仅能够阻隔细菌，使得脂肪干细胞和皮肤伤口保持一个潮湿环境，提供一个良好的修复环境，降低免疫排斥反应，而且能够避免更换贴片时，贴片与伤口粘连从而保护新生皮肤组织，不仅实现快速修复皮肤的目的，而且能够减轻患者痛苦，不易造成创伤部位色素累积形成疤痕等。
摘要（英）：

The invention relates to a preparing method of a skin patch for repairing a skin burn. The preparing method comprises the following steps that adipose-derived stem cells and an allogenic skin matrix are obtained; the adipose-derived stem cells and hydrogel are mixed and inoculated to the allogenic skin matrix, wherein the adipose-derived stem cells are from the body of a patient suffering from the skin burn, and the hydrogel is prepared by mixing an alginate solution and a gelatin solution. The adipose-derived stem cells are carried in the hydrogel prepared from alginate and gelatin so that bacteria can be blocked, a humid environment is maintained for the adipose-derived stem cells and the skin wound, a good repair environment is provided, and immunological rejection is relieved; in addition, adhesion of the patch and the wound can be prevented when the patch is replaced, and thus the new skin tissue can be protected; the purpose of quickly repairing the skin can be achieved, the pain of the patient can also be relieved, and the phenomena of a scar caused by pigment accumulation at the wound part and the like are not likely to occur.

0/0