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发明授权
CN105603113B HIV-1早期感染相关的血清miRNA在制备试剂盒中的应用 失效 - 权利终止

HIV-1早期感染相关的血清miRNA在制备试剂盒中的应用
摘要：
本发明属于生物技术领域，具体涉及一种基于血清miRNA的试剂盒及其使用方法在HIV‑1感染早期检测中的应用。本发明涉及的miRNA分子包括hsa‑miR‑29a、hsa‑miR‑223、hsa‑miR‑27a、hsa‑miR‑19b、hsa‑miR‑151‑3p、hsa‑miR‑28‑5p、hsa‑miR‑766、hsa‑miR‑30a‑5p和hsa‑miR‑136*。用这9种血清miRNA作为分子靶标，建立了一种快速、敏感、特异的HIV‑1感染早期的检测方法。本发明涉及上述9种miRNA在病毒感染早期诊断中的用法及检测这9种miRNA所用的试剂盒。
摘要（英）：

The invention belongs to the field of biotechnology and particularly relates to a kit based on serum miRNA and an application thereof in early detection of HIV-1 infection. The miRNA molecules involved in the invention include hsa-miR-29a, has-miR-223, hsa-miR-27a, hsa-miR-19b, hsa-miR-151-3p, hsa-miR-28-5p, hsa-miR-766, hsa-miR-30a-5p and hsa-miR-136*. A quick, sensitive and specific detection method for early detection of HIV-1 infection is established by adopting the 9 kinds of serum miRNA as molecular targets. The invention relates to an application method of the 9 kinds of miRNA in early diagnosis of virus infection and a kit for detecting the 9 kinds of miRNA.

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