A key-shaped vibration isolation cushion used at the lower portion of a track traffic track bed slab comprises a board-shaped cushion body and at least one vibration isolation region located on the cushion body. Each vibration isolation region comprises multiple vibration isolation keys. Each vibration isolation key is in a truncated cone shape to achieve a good pressure bearing effect. The vibration isolation regions comprise the first vibration isolation region, the second vibration isolation region and the third vibration isolation region. The first vibration isolation region and the second vibration isolation region are spaced by a certain distance to form a first groove. The second vibration isolation region and the third vibration isolation region are spaced by a certain distance to form a second groove. Therefore, a key-shaped structure is adopted by the vibration isolation cushion, the nonlinearity characteristic of a vibration damping material is brought into full play, key-shaped elastic bodies are distributed to better adapt to different structural forms, and the key-shaped vibration isolation cushion can meet the requirements of a common-speed railway, urban track traffic, a high-speed railway and a heavy haul railway for different loads and different degrees of displacement.