The invention relates to an intelligent dispatching system and method for a multi-AGV (Automatic Guided Vehicle) of an automatic container terminal. The two-stage distribution control dispatching mode of an operation plan and dispatching decoupling separation is realized through a container terminal management information system and an AGV group intelligent dispatching system. A knowledge learning method is used; an AGV dispatching knowledge management module is built; an AGV task case base, a path case base and a knowledge base are continuously enriched and optimized; and the AGV self learning, self organization and self decision capability are improved. Through the rolling prediction on traffic flow in a road network space of the automatic container terminal and the calling of the knowledge base, the AGV task case base and the path case base, the collaborative optimization is performed on the task dispatching and the path planning of AGVs. The invention provides an AGV path planning strategy including the optional path and free path mode; the path plan in the conventional task can be ensured; and the fast response measures can also be provided for emergency tasks.